Clone Number: ENA2
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: 100 ug/ ml
Storage buffer: PBS with 0.1% BSA and 0.02% sodium azide
Additional info: ENA2 reacts with E-selectin CD62-E, previous designated the Endothelial Leucocyte Adhesion Molecule-1 (ELAM-1). The antibody reacts with human endothelial cells activated with TNF-alpha, IL-1 or endotoxin. The antibody was found to react also with cells transfected with the E-selectin gene. The antibody inhibits the adhesion of granulocytes both neutrophilic and eosinophilic.
References: Leeuwenberg; JFM et al. Eur J Immunol 1989; 19: 715 /Leeuwenberg, JFM et al Clin and Exp Immunol 1990, 81: 496 /Leeuwenberg; JFM et al. Immunology 1990; 71: 301