Mouse anti-FLI-1, clone MRQ-1 (Monoclonal)

Clone Number: MRQ-1

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Friend leukemia integration 1 transcription factor (FLI-1) is a protein encoded by the proto-ocogene FLI1. The FLI-1 protein is best known for its critical role in the pathogenesis of ES/pPNET. FLI-1 is normally expressed in endothelial cells and in hematopoietic cells, including T-lymphocytes. The immunohistochemical detection of FLI-1 protein has been shown in studies to be valuable in the discrimination of Ewing sarcoma/peripheral primitive neuroectodermal tumor (ES/pPNET) from most of its potential mimics. ES/pPNET is a rare primary tumor of the bone/soft tissue that resembles other undifferentiated tumors.

References: Mhawech-Fauceglia P, et al. Histopathology. 2006; 49:569-75/Kuroda N, et al. Med Mol Morphol. 2006; 39:221-5/Ellison DA, et al. Hum Pathol. 2007; 38:205-11

• Artikelnummer: SANMON3280
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON3280
• Green Labware: Nein
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2b
• Wirt: Mouse