Mouse anti-HCAM, CD44, clone DF 1485 (Monoclonal)

Clone Number: DF1485

Immunogen: CD44 antigen (PGp-1) purified from lymphocyte membrane

Concentration: n/a

Storage buffer: Contains 0.09% sodium azide

Additional info: CD44 (HCAM) is a transmembrane protein expressed by lymphocytes, erythrocytes and several normal epithelial cells and is a member of the CAM family. It is involved in lymphocyte homing, T-lymphocyte activation, interaction with hyaluronic acid and may act as an adhesion molecule. The human CD44 is composed of 19 exons, 9 variably expressed due to alternative splicing of mRNA; RT CD44 (CD44s) is composed of exons 1-5 and 15-19. The loss of CD44s expression predicts unfavorable outcome in bladder cancers, squamous cell carcinomas of the skin, prostatic adenocarcinoma and neuroblastomas. In immunoblotting the antibody reacts with a glycoprotein isolated from hematopoetic cells and epithelial cells with a respective molecular weight of 29-37 kD and 51 kD.Positive control: Tonsil (cell membrane staining).

• Artikelnummer: SANMON8036
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON8036
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Western Blotting, Flow Cytometry
• Isotyp: IgG1
• Wirt: Mouse
• Konjugat: Unconjugated