Mouse anti-Hu CD134 Purified, clone Ber-ACT35 (Monoclonal)

Clone Number: Ber-ACT35

Immunogen: HTLV 1-transformed HUT-102 cells

Concentration: 1 mg/ml

Format: Purified by protein-A affinity chromatography.

Storage buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Additional info: CD134 (TNFRSF4, also known as OX40) is a type I transmembrane glycoprotein of TNF/NGF receptor family expressed on activated T cells, fibroblasts, and hematopoietic precursors. Binding to its ligand (OX40L, TNFSF4) on antigen presenting cells gives to the T cell costimulatory signal, and this interaction results also in B cell proliferation and influences T cell memory pool. CD134 is upregulated at sites of inflammation, especially in case of multiple sclerosis and psoriatic lesions.SpecificityThe mouse monoclonal antibody BV10A4 (BV10) reacts with an extracellular epitope of CD135 (FLT3, FLK2, STK-1), a 130-160 kDa type I transmembrane receptor tyrosine kinase that is involved in early steps of hematopoiesis.Application detailsFlow cytometry: Recommended dilution: 3-6 μg/ml.
Immunohistochemistry: Recommended dilution: 5-10 μg/ml.

• Artikelnummer: SANMON23086
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23086
• Green Labware: Nein
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Human, Primate
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Immunoprecipitation, Western Blotting, ELISA, Flow Cytometry
• Isotyp: IgG1 kappa
• Wirt: Mouse