Mouse anti-Hu CD16 Purified, clone MEM-168 (Monoclonal)

Clone Number: MEM-168

Immunogen: Human granulocytes

Concentration: 1 mg/ml

Format: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Storage buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Additional info: CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms – FcgammaRIII-A and -B. FcgammaRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated, moreover, with FcepsilonRI-beta subunit. Besides IgG, FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.SpecificityThe mouse monoclonal antibody BY55 recognizes an extracellular epitope of CD160, a 27 kDa glycoprotein expressed on NK cells, NK-T cells, intestinal intraepithelial lymphocytes, TCR-gamma/delta T cells and a small population of TCR-alpha/beta T cells. The antibody detects both GPI-anchored and transmembrane form of CD160.Application detailsFlow cytometry: Recommended dilution: 1-4 μg/ml.

• Artikelnummer: SANMON23106
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23106
• Green Labware: Nein
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Human, Primate, Pig (Porcine)
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgM
• Wirt: Mouse