Mouse anti-Hu CD195 Purified, clone T21/8 (Monoclonal)

Clone Number: T21/8

Immunogen: CCR5 peptide (Met1-Lys22) KLH conjugate

Concentration: 1 mg/ml

Format: Purified by protein-A affinity chromatography.

Storage buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Additional info: CD195 / CCR5 (also known as CKR-5) is a receptor for inflammatory CC-chemokines (characterized by a pair of adjacent cysteine residues), such as MIP-1 alpha, MIP-1 beta, or RANTES. It is a G protein-associated seven-pass transmembrane protein expressed on resting T cells with memory/effector phenotype, monocytes, macrophages and immature dendritic cells. This chemokine receptor regulates the activation and directed migration of leukocytes. Importantly, along with CD4, CD195 / CCR5 functions as a major receptor for HIV. Their ligand is the viral glycoprotein gp120.SpecificityThe mouse monoclonal antibody C9Mab-1 recognizes an extracellular epitope of CD199, a 7-transmembrane chemokine receptor.Application detailsWestern blotting: Do not boil cell lysates prior to SDS-PAGE.
Flow cytometry: Recommended dilution: 1-4 µg/ml

• Artikelnummer: SANMON23128
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23128
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Western Blotting, ELISA, Flow Cytometry, Immunocytochemistry
• Isotyp: IgG1 kappa
• Wirt: Mouse
• Konjugat: Unconjugated