Mouse anti-Hu CD35 Purified, clone E11 (Monoclonal)

Clone Number: E11

Immunogen: Acute monocytic leukemia cells and normal blood monocytes

Concentration: 1 mg/ml

Format: Purified by protein-A affinity chromatography.

Storage buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Additional info: CD35 (complement receptor 1, CR1) is a monomeric multiple modular cell surface glycoprotein which serves as receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. It is expressed mainly on the surface of granulocytes, monocytes, erythrocytes, B cells and folicular dendritic cells. Besides its role in complement cascade, CD35 is involved in blocking BCR-induced proliferation and the differentiation of B cells to plasmablasts and their Ig production.SpecificityThe mouse monoclonal antibody hsF6.4.20 recognizes an extracellular epitope of CD352, a transmembrane glycoprotein expressed on NK, T and B cells.Application detailsImmunohistochemistry (paraffin sections): Heat mediated antigen retrieval.
Immunohistochemistry (frozen sections): Acetone fixation.
Flow cytometry: Recommended dilution: 1-4 µg/ml

• Artikelnummer: SANMON23184
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23184
• Green Labware: Nein
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Human, Primate
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Immunoprecipitation, Western Blotting, Flow Cytometry, Immunocytochemistry
• Isotyp: IgG1
• Wirt: Mouse