Mouse anti Human bax

Mouse anti Human bax, Monoclonal, IgG1, Clone: 2D2

Clone: 2D2

Background: The immunogen for the anti-h bax was a synthetic peptide corresponding to amino acids 3 to 16 of the human bax sequence. Bax expression is associated with cell death regulation. The ratio of bax to other bcl-2 family members is believed to regulate apoptosis.

Immunogen: A synthetic peptide corresponding to amino acids 3 to 16 of the human bax sequence

Purification Method: Protein A/G Chromatography

Concentration: See vial for concentration

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

References: 1. Y.T. Hsu et. al. (1997) J. Biol. Chem., 272(21): 13829-13834 2. Y. T. Hsu et. al (1997) Proc. Natl. Acad. Sci. USA, 94: 3668-3672 3. Annis, M., et al, 'Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis' EMBO Journal 2005, 24, , 2096-21034. Soucie, E.L., et al, 'Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria' Molecular and Cell Biology 2001, 21, , 4725-4736

UniProt: Q07812 - Bax-alphaQ07814 - Bax-beta

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAA100M
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: A100M
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Western Blotting
• Isotyp: IgG1
• Wirt: Mouse
• Konjugat: Unconjugated