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DENND4C Antibody: ATTO 594
Mouse Anti-Human DENND4C Monoclonal IgG1
Artikelnummer
STRSMC-610D-A594
Verpackungseinheit
100 µg
Hersteller
Stressmarq Biosciences
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Target: DENND4C.
Conjugate: ATTO 594.
Product Type: Monoclonal.
Clone Number: 3E8.
Immunogen: Full Length Human Recombinant Dennd4c protein.
Swiss-Prot: Q5VZ89.
Purification: Protein G Purified.
Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide.
Concentration: 1mg/ml.
Specificity: Detects ~213 kDa.
Cellular Localization: Cell membrane , Cytoplasm , Cytoplasmic vesicle , Membrane.
Tissue Specificity: Widely expressed.
Scientific Background: Dennd4c is a guanine nucleotide exchange factor (GEF) for Rab10, and required for GLUT4 translocation (1). It is associated with Alkuraya-Kucinskas Syndrome and Koolen-De Vries Syndrome (2) and interacts with the retromer (3).
References: 1. Sano, H. et al. (2011). J Biol Chem. 286(19):16541-5.2. https://www.genecards.org/cgi-bin/carddisp.pl?gene=DENND4C3. McMillan, K. et al. (2016). J Cell Biol. 214(4):4389–404.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Conjugate: ATTO 594.
Product Type: Monoclonal.
Clone Number: 3E8.
Immunogen: Full Length Human Recombinant Dennd4c protein.
Swiss-Prot: Q5VZ89.
Purification: Protein G Purified.
Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide.
Concentration: 1mg/ml.
Specificity: Detects ~213 kDa.
Cellular Localization: Cell membrane , Cytoplasm , Cytoplasmic vesicle , Membrane.
Tissue Specificity: Widely expressed.
Scientific Background: Dennd4c is a guanine nucleotide exchange factor (GEF) for Rab10, and required for GLUT4 translocation (1). It is associated with Alkuraya-Kucinskas Syndrome and Koolen-De Vries Syndrome (2) and interacts with the retromer (3).
References: 1. Sano, H. et al. (2011). J Biol Chem. 286(19):16541-5.2. https://www.genecards.org/cgi-bin/carddisp.pl?gene=DENND4C3. McMillan, K. et al. (2016). J Cell Biol. 214(4):4389–404.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
| Artikelnummer | STRSMC-610D-A594 |
|---|---|
| Hersteller | Stressmarq Biosciences |
| Hersteller Artikelnummer | SMC-610D-A594 |
| Green Labware | Nein |
| Verpackungseinheit | 100 µg |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus) |
| Klonalität | Monoclonal |
| Methode | Immunofluorescence, Immunoprecipitation, Western Blotting, Immunocytochemistry |
| Isotyp | IgG1 |
| Human Gene ID | 55667 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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