Mouse anti Human myc

Mouse anti Human myc, Monoclonal, IgG1, Clone: 33

Clone: 33

Background: Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several types of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64kDa and 67kDa, the unphosphorylated form is 49kDa.

Purification Method: Protein A/G Chromatography

Concentration: See vial for concentration

Source: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant full-length human c-Myc protein and mouse myeloma cells.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

References: 1) K. Alitala et. al. (1983) Proc. Natl. Acad. Sci., 80: 1707-1711 2)H. Person et.al. (1984) Science 225 687-693

UniProt: P01106 (Human)P01108 (Mouse)P09416 (Rat)

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAN115M
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: N115M
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Bird (Avian)
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Western Blotting, Immunohistochemistry
• Isotyp: IgG1
• Wirt: Mouse
• Konjugat: Unconjugated