Mouse anti Human p16 - ink4a

Mouse anti Human p16 - ink4a, Monoclonal, IgG1, Clone: DCS50.1

Clone: DCS50.1.

Background: The immunogen for the anti-human p16 was a recombinant full length p16 protein recognizing a 16kDa protein. The p16ink4a tumor suppressor protein shows no cross reactivity with the closely related inhibitors such as p15ink4b and p18ink4c. p16ink4a is a specific inhibitor of cdk4/cdk6, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including melanoma and lung carcinoma. It can be used in immunohistochemistry as an indicator of HPV infection in cervical and head and neck (pre)malignancies.

Immunogen: A recombinant full length p16 protein recognizing a 16kDa protein.

Purification Method: Protein A/G Chromatography.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.

References: 1) J. Lukas et.al (1995) Nature., 375,503-506

2) L. Aagaard et.al. (1995), Intl. J. of Cancer 61(1) 115-120.

UniProt: P42771 (Human).

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAC170M
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: C170M
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Western Blotting, Immunohistochemistry
• Isotyp: IgG1
• Wirt: Mouse