Mouse anti-Human p27, clone SX53G8 (Monoclonal)

Clone Number: SX53G8

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: p27, also known as cyclin-dependent kinase inhibitor 1B (CDNK1B), is a kinase inhibitor that controls cell cycle progression.1-4 p27 is involved in G1 phase arrest and obstructs cell entry into the S phase by binding to and inhibiting cyclin E-CDK2, effectively slowing or stopping the cell division cycle.1-4 p27 is broadly expressed in normal tissue but can be dysfunctional in neoplastic tissue and, therefore, not expressed.

References: Polyak K, et al. Cell. 1994; 78:59-66/Sun C, et al. AM J Cancer Res. 2016; 6:2207-20/Sangfelt O, et al. Oncogene. 1999; 18:2798-810

• Artikelnummer: SANMON3326
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON3326
• Green Labware: Nein
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1-k
• Wirt: Mouse