Mouse anti-MALT1, clone EBS-T-007 (Monoclonal)

Clone Number: EBS-T-007

Immunogen: human MALT1 recombinant protein

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: EBS-T-007 reacts with paracaspase MALT1, crucial for B- and T-cell activation/proliferation and activation of transcription factor NF-B. It has an N-terminal death domain, two central immunoglobulin-like domains involved in the binding to the B-cell lymphoma 10 (BCL10) protein and a caspase-like domain. MALT1 and BCL10, can both be found translocated in MALT lymphoma. In such cases either BCL10 or MALT1 or both are highly expressed, depending on the site of translocation. Normal cells and MALT lymphomas lacking translocations exhibit much lower levels of expression.

References: Ye H, et al, Am J Pathol 157: 1147-54 (2000)

• Artikelnummer: SANMON9912
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9912
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Western Blotting
• Isotyp: IgG1-k
• Wirt: Mouse
• Konjugat: Unconjugated