Clone Number: VU-3C6
Immunogen: ZR-75-1 breast cancer cells
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: VU-3C6 reacts with the protein core of MUC1, an apical cell side epithelial marker which is upregulated or switched on in the majority of carcinomas. The dominant epitope of VU-3- C6 is GVTSAPDTRPAP, located in the VNTR domain of MUC1. Binding of VU-3C6 is enhanced after glycosylation of the DTR motif.
References: ISOBM TD-4 Workshop report, Tumor Biol. 19(Suppl 1) (1998)/Karsten, U. et al. Cancer. Res. 58(12): 2541-2549 (1998)/Ryuko, K. et al. Tumor Biol. 21(4): 197-210 (2000)