Clone Number: MRQ-60
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Napsin is a pepsin-like aspartic proteinase in the A1 clan of the AA clade of proteinases. There are two closely related napsins, napsin A (NAPSA) and napsin B (NAPSB). Napsin A is involved in processing propeptide pulmonary surfactant protein B (proSP-B) in the lung. In normal tissue, Napsin A is expressed in type II pneumocytes of the lung and proximal tubules of the kidney. Napsin A is a useful marker for lung adenocarcinoma.
References: Jagirdar J. Arch Pathol Lab Med.; 132:384-96 (2008)/Bishop JA, et al.. Hum Pathol.; 41:20-5 (2010)/Ye J, et al. Appl Immunohistochem Mol Morphol.; 19:313-17 (2011)