Clone Number: N52.1.7
Immunogen: Carboxy-terminal segment of enzymatically dephosphorylated porcine neurofilament H (NF-H) polypeptide.
Concentration: Greater than or equal to 95 mg/L
Storage buffer: Tissue culture supernatant with sodium azide
Additional info: Neurofilaments constitute the main structural elements of neuronal axons and dendrites. Neurofilaments are composed of three major subunits referred to as the neurofilament triplet, with molecular weights of 68 kD, 160kD and 200 kD. Within tumors, only neoplastic cells of neural origin or those exhibiting neuronal differentiation, have been reported to express neurofilaments. NF-H (200 kD) polypeptide of human neurofilament. This antibody reacts with both phosphorylated and unphosphorylated forms of NF-H.
References: Lovas G et al. Brain. 2000; 123:308-317