Mouse anti-p53, clone DO7

Clone Number: DO7

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: The antibody recognizes a 53 kDa phosphoprotein, identified as p53 suppressor gene product. It reactswith the mutant as well as wild type p53.1 Positive nuclear staining with this antibody has been shownto be a factor in breast carcinoma, lung carcinoma, colorectal carcinoma, urothelial carcinoma, andependymoma.2-8 Anti-p53 positivity has also been used to differentiate uterine serous carcinomafrom endometrioid carcinoma, as well as a marker for intratubular germ cell neoplasia.

References: Mauri FA et al. Int J Oncol 1999 Dec;15(6):1137-47/Caffo O et al. Clin Cancer Res 1996 Sep;2(9):1591-9/Bebenek M et al. Anticancer Res 1998 Jan-Feb;18(1B):619-23

• Artikelnummer: SANMON-RTU1168
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON-RTU1168
• Verpackungseinheit: 7 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2b-k
• Wirt: Mouse
• Konjugat: Unconjugated