Mouse anti-PD-L1, clone 405.9A11 (Monoclonal)

Clone Number: 405.9A11

Immunogen: Last 19 aa of human membrane-bound PDL1 polypeptide, couple to KLH

Concentration: lot specific

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: The programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses. Many cancer types express PD-L1 and evade immune recognition via the PD-1/PD-L1 interaction. Precision therapies targeting the PD-1/PD-L1 pathway have the potential to improve response and thereby offer a novel treatment avenue to some patients with cancer.

References: Cree et al. HistoPath 2016;69(2):177-186/Garon et al. N Engl J Med 2015;372(21):2018-2028

• Artikelnummer: SANMON9984
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9984
• Green Labware: Nein
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1k
• Wirt: Mouse