Mouse anti-Progesterone Receptor, clone 16 (monoclonal)

Clone Number: 16

Immunogen: Prokaryotic recombinant protein corresponding to the N-terminal region of the A form of the human progesterone receptor.

Concentration: Greater than or equal to 324 mg/L

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: The human progesterone receptor (PR) is expressed as two isoforms, PRA (94 kD) and PRB (114 kD), which function as ligand-activated transcription factors. These two isoforms are transcribed from distinct estrogen receptor (ER)-inducible promoters within a single copy PR gene. Clone 16 is specific for a region of the N-terminus of the A form of PR. The precise epitope has not been mapped but it reacts with both A and B forms of PR by Western blot but only with the A form by immunohistochemistry. This suggests that the epitope is inaccessible in the native folded B form of the protein.

References: Hungermann D et al. Journal of Pathology 2002; 198: 487–494

• Artikelnummer: SANMONX10118
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MONX10118
• Green Labware: Nein
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1
• Wirt: Mouse