Mouse anti-TGF-alpha, clone 1E8-G6 (Monoclonal)

Clone Number: 1E8-G6

Immunogen: synthetic TGF-alpha 34-43 decapeptide linked carrier

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: 1E8-G6 reacts with TGF-alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. 1E8-G6 is completely blocked by the peptide used for immunization. TGFalpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype. In sections both cytoplasma and cell membranes are stained

References: Bebók, Zs, et al. Breast Cancer Res.Treatm. 29: 229-235 (1994)

• Artikelnummer: SANMON9841
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9841
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Rabbit, Zebrafish
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Western Blotting, ELISA, Flow Cytometry
• Isotyp: IgM-k
• Wirt: Mouse