Mouse Exodus-2 Recombinant

Mouse Exodus-2 Recombinant
Artikelnummer
BPS90131-A
Verpackungseinheit
5 µg
Hersteller
BPS Bioscience

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Encompassing Amino Acids: 24-133

Amino Acid Sequence: SDGGGQD CCLKYSQKKI PYSIVRGYRK QEPSLGCPIPAILFSPRKHS KPELCANPEE GWVQNLMRRL DQPPAPGKQS PGCRKNRGTS KSGKKGKGSKGCKRTEQTQP SRG

Background: Exodus-2, which is a member of the family of CC- Chemokines, has a unique 36 (murine) or 37 (human) amino acid carboxyl-terminal extension not seen in other chemokines. Exodus-2 selectively stimulates the chemotaxis of adult T-lymphocytes and is expressed preferentially in lymph node tissue. Exodus-2 is critical for adult T-cell adhesion to high endothelial venules in lymph nodes, a rate-limiting step for T-cell trafficking through nodal tissue.

Biological Activity: Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10.0-100.0 ng/ml.

Description: Recombinant mouse Exodus-2 is a disulfide-linked homodimeric protein consisting of 111 amino acid residues, and migrates as an approximately 12 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding murine Exodus-2 mature chain was expressed in E. coli.

Endotoxin Level: <0.1 ng/µg (1 EU/µg), using the LAL gel clot method.

Format: lyophilized protein

Formulation: Lyophilized from 0.2 µm filtered PBS solution.

Genbank: P84444

Purity: ≥95% by SDS-PAGE and HPLC

Reconstitution: Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.

Storage Stability: The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.

Uniprot: P84444

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: J. Exp. Med., Jan 2000, 191: 61.
Mehr Informationen
Artikelnummer BPS90131-A
Hersteller BPS Bioscience
Hersteller Artikelnummer 90131-A
Verpackungseinheit 5 µg
Mengeneinheit STK
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