Clone: MPO-1/1, 7.17.
Conjugate: PE.
Immunogen: Purified human MPO.
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
Description: This antibody reacts with the intracellular enzyme, myeloperoxidase in peripheral blood granulocytes on cytospots in a characteristic granular pattern. Monocytes are negative or slightly positive while eosinophils and lymphocytes are negative. MPO antibodies stain promyelocytes, myelocytes, metamyelocytes and mature neutrophil granulocytes in bone marrow.
MPO is a tetrameric protein, each tetramer contains a two 60 kD heavy units and two 12 kD light units. It is a lysosomal hemoprotein stored in azurophilic granules.