Product Type: Inhibitor
CAS No.: 209783-80-2
MolecularFormula: C21H20N4O3
Molecular Weight: 376,41
Source: Synthetic
Purity: >98.5
Solubility: Soluble in DMSO or methanol.
Appearance: Off white solid
PubChem CID: 4261
Scientific Background: MS 275, also referred to as Entinostat, is a benzamide histone deacetylase inhibitor. It preferentially inhibits HDAC1 and HDAC3. It is currently undergoing several clinical trials for the treatment of Hodgkin's lymphoma, advanced breast cancer, and for metastatic lung cancer.
References: 1. Camphausen K., Burgan W., Cerra M., Oswald K.A., Trepel J.B., Lee M.J., et al. (2004) Cancer Res. 316-21.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.