MS4A2 Polyclonal Antibody, Rabbit

Abbreviation: MS4A2

Target Synonym: MS4A2;APY;ATOPY;FCER1B;FCERI;IGEL;IGER;IGHER;MS4A1

Conjugation: Unconjugated

UNIProt ID: Q01362

Background: The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human MS4A2

Dilution: WB 1:500-1:2000

• Artikelnummer: ELSE-AB-92885-120
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-92885-120
• Green Labware: Nein
• Verpackungseinheit: 120 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit