Clone Name: G219-1129
Light Chain: Kappa
Application Note: IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 105
Positive Control: Colon carcinoma
Form: Liquid
Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Uniprot ID: P43246
Antigen Species: Human
Immunogen: BALB/C mice were injected with recombinant human MSH2 protein
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: mutS homolog 2