English
MSH6 antibody (ZM99)
MSH6 antibody (ZM99)
Artikelnummer
GTX01751-500
Verpackungseinheit
500 μl
Hersteller
GeneTex
Verfügbarkeit:
wird geladen...
Preis wird geladen...
Clone Name: ZM99
Light Chain: Kappa
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 153
Positive Control: Colon carcinoma
Form: Liquid
Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
Uniprot ID: P52701
Antigen Species: Human
Immunogen: Recombinant fragment of human MSH6 protein (around aa 374-540)
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: mutS homolog 6
Light Chain: Kappa
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 153
Positive Control: Colon carcinoma
Form: Liquid
Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
Uniprot ID: P52701
Antigen Species: Human
Immunogen: Recombinant fragment of human MSH6 protein (around aa 374-540)
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: mutS homolog 6
| Artikelnummer | GTX01751-500 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX01751-500 |
| Green Labware | Nein |
| Verpackungseinheit | 500 μl |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (paraffin) |
| Isotyp | IgG2b |
| Human Gene ID | 2956 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
Verwandte Artikel
Markieren Sie die Artikel, um Sie dem Warenkorb hinzuzufügen oder
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
