NAPE-PLD (Internal) Polyclonal Antibody

Formulation: 500 µl of peptide affinity-purified polyclonal antibody

Immunogen: Synthetic peptide from an internal region of human protein NAPE-PLD

Shelf life (days): 1095

Notes: N-acylethanolamines (NAEs) are involved in diverse biological processes such as inflammatory regulation, apoptosis, and tissue degeneration.{12164} In animals, NAEs are mainly biosynthesized via a membrane phospholipid-dependent pathway, which is the enzymatic hydrolysis of N-acyl-phosphatidylethanolamine (NAPE). The enzyme catalyzing this reaction is a phospholipase D subtype selective for NAPE named N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D (NAPE-PLD). It has been cloned from mouse, rat, and human and is 393-396 amino acids in length, with an estimated molecular weight of 46 kDa. Both NAPE-PLD mRNA and protein activity have been detected in a wide range of tissues with the highest levels in brain, kidney, and testis.{11963} In rat, NAPE-PLD activity in the brain is low in neonates and is 15-fold higher in adults, whereas the activity remains constant in the heart during development.{13170}

• Artikelnummer: CAY10305-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10305-500
• Green Labware: Nein
• Verpackungseinheit: 1 ea (500 µl)
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting
• Wirt: Rabbit