Product Type: Inhibitor
CAS No.: 54527-84-3
MolecularFormula: C26H29N3O6•HCl
Molecular Weight: 515,99
Source: Synthetic
Purity: >98%
Solubility: Soluble in DMSO (1 mg/ml), ethanol:water 25:75-70:30, propylene glycol, or methanol; slightly soluble in acetone, 100% ethanol, chloroform and water.
Appearance: Yellow solid
PubChem CID: 41114
Scientific Background: Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders such as chronic stable angina, hyptertension and Raynaud's phenomenon. Its mechanism of acion is to inhibit the transmembrane influx of calcium ions into the cardiac muscle and smooth muscle without changing the serum calcium concentrations.
References: 1. Huang R.I., et al. (2006) Catheter Cardiovasc Interv. 68(5): 671-676.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.