Product Type: Inducer
CAS No.: 28643-80-3
MolecularFormula: C40H67NaO11
Molecular Weight: 746,94
Source: Synthetic
Purity: >98%
Solubility: Soluble to 50 mM in DMSO and 20 mM in ethanol
Appearance: White to off-white Solid
PubChem CID: 23681158
Scientific Background: Nigericin acts as a K and Na ionophore. It stimulates Ca release from mitochondrial stores by disruption of membrane potential.
References: 1. Vercesi A.E., et al. (1993) J Biol Chem. 268: 8564.2. Graven S.N., Estrada-O, S., Lardy H.A. (1966) Proc Natl Acad Sci USA. 56(2): 654-658.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.