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Encompassing Amino Acids: 22-258
Description: Human NKp46, also known as CD335, Natural Cytotoxicity Triggering Receptor 1, Lymphocyte Antigen 94 Homolog, and Natural Killer Cell P46-Related Protein, GenBank Accession No. NM_004829, a.a. 22-258, fused at the C-terminus with the Fc portion of human IgG1 followed by a C-terminal Avi-tag™ and expressed in a HEK293 cell expression system. MW=56 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation. This protein is enzymatically biotinylated using Avi-Tag technology. Biotinylation is confirmed to be ≥90%.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_004829
Storage Stability: Stable for at least 6 months at -80°C
Supplied As: Aqueous Buffer Solution
Tags: C-terminal Fc-Avi-Tag
Uniprot: O76036
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Mandelboim, O., et al., Nature. 2001 Feb; 409: 1055-1060. 2. Mandelboim, O., et al., The Int’l J. of Biochem. & Cell Bio. 2001 Jul; 33(12): 1147-1150