Clone Name: AT5F4
Light Chain: Kappa
Calculated MW: 17
Specificity/Sensitivity: Based on internal testing result, this antibody does not cross react with human NME2, human NME3, and human NME4.
Form: Liquid
Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
Uniprot ID: P15531
Antigen Species: Human
Immunogen: The clone AT5F4 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NME3 protein.
Purification: Protein A Purified
Conjugation: Unconjugated
Full Name: NME/NM23 nucleoside diphosphate kinase 1