NpFR1

Reversible fluorescence intensity-based redox sensor

Product Type: Redox Probe

MolecularFormula: C23H21N5O4

Molecular Weight: 431,45

Source: Synthetic

Solubility: Soluble in DMSO

Appearance: Red Solid

Scientific Background: NpFR1, or napthalimide-flavin redox sensor 1, is a novel flavin molecule that exhibits a greater than 100-fold increase in fluorescence upon oxidation, and is easily reversible. In the oxidative form, is shows a maximum absorption at 395 and 463nm, max admission at 545nm. Treatment with a mild reducing agent (including sodium thiosulfate, sodium cyanoborohydride, DTT and glutathione) gave the reduced form which exhibited 110-fold lower absorbance, and 125-fold lower emission. Re-oxidation to its original fluorescence can be achieved by air or by hydrogen peroxide.

References: 1. Yeow J., Kaur A.K., Anscomb M.D., and New E.J. (2014) Chem. Commun. 50: 8181-8184.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-181-1MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-181-1MG
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK