NSC 668394, CAS 382605-72-3

Formulation: A solid

Formal Name: 7-[[2-(3,5-dibromo-4-hydroxyphenyl)ethyl]amino]-5,8-quinolinedione

Purity: ≥98%

Formula Markup: C17H12Br2N2O3

Formula Weight: 452,1

Shelf life (days): 1460

CAS Number: 382605-72-3

Notes: NSC 668394 is a binder of ezrin (Kd = 10.6 µM).{27163} It inhibits PKCι-induced phosphorylation of ezrin in a cell-free assay (IC50 = 8.1 µM).{66915} NSC 668394 (10 µM) inhibits the interaction between ezrin and actin in K7M2 osteosarcoma cells. It inhibits the migration and invasion of K7M2 cancer cells when used at a concentration of 2 µM.{27163} NSC 668394 (10 µM) reduces bacterial invasion but is not bactericidal in HEp-2 cells infected with group A Streptococcus (GAS).{66916} It induces developmental delays and cyclopia in Xenopus larvae when used at a concentration of 10 µM and induces toxicity at 40 µM.{66915}

• Artikelnummer: CAY16863-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16863-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK