OCT-2 (POU2F2) (B-Cell Marker) (OCT2/2137), 1mg/mL

OCT-2 (POU2F2) (B-Cell Marker) (OCT2/2137), 1mg/mL
Artikelnummer
BTMBNUM2137-50
Verpackungseinheit
50 uL
Hersteller
Biotium

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Description: Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of Oct-2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: OCT2/2137

Entrez Gene ID: 5452

Immunogen: Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)

Verified AB Applications: IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: IHC, FFPE (verified)/WB (verified)
Mehr Informationen
Artikelnummer BTMBNUM2137-50
Hersteller Biotium
Hersteller Artikelnummer BNUM2137-50
Verpackungseinheit 50 uL
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Western Blotting, Immunohistochemistry
Isotyp IgG1 kappa
Wirt Mouse
Konjugat Unconjugated
Produktinformation (PDF) Download
MSDS (PDF) Download