Optiferrin

Product Description
Optiferrin® is a high-purity recombinant human transferrin (rTf), designed as a chemically defined, blood-free alternative to human holo transferrin for cell culture, stem cell expansion, and bioproduction applications. Engineered to deliver equivalent or superior performance to plasma-derived transferrin, Optiferrin provides unmatched regulatory advantages, safety, and consistency, making it ideal for serum-free and animal-free media formulations.
Manufactured in an ISO 9001:2015-certified, cGMP-compliant facility in the United States, Optiferrin ensures batch-to-batch consistency, pathogen safety, and scalability for research and industrial applications.

Advantages

• Optimized for Serum-Free, Animal-Origin-Free Cell Culture
  • Fully recombinant, blood-free human transferrin – ensuring consistent performance without batch variability.
  • Equivalent to human holo transferrin in supporting cell growth, proliferation, and iron homeostasis.
  • Improves cell viability and metabolic activity in a wide range of cell culture applications.
• Animal-Origin-Free Assurance
  • 100% chemically defined and animal-origin-free (AOF) – eliminating risks associated with plasma-derived transferrin.
  • Manufactured using a non-animal, non-human host system, ensuring purity and reproducibility.
  • Raw materials, manufacturing equipment, and packaging are fully animal-free, aligning with regulatory and ethical standards.
• Manufactured in the United States
  • Produced in a tertiary-level, ISO 9001:2015-certified facility in the USA.
  • Complete supply and manufacturing chain is owned and operated by InVitria, ensuring unmatched traceability and quality control.
  • Batch-to-batch consistency for reliable integration into cGMP bioproduction workflows.
• Ready-to-Use Lyophilized Format
  • Supplied as a lyophilized powder, providing long-term stability and easy reconstitution.
  • Flexible formulation to support a wide range of cell culture applications.
  • Eliminates variability associated with plasma-derived transferrin, enabling chemically defined media development.

Applications

• Cell Culture & Bioproduction
  • Supports CHO, HEK, VERO, and other mammalian cell lines, optimizing biopharmaceutical and vaccine production.
  • Enables serum-free and chemically defined media for more consistent, reproducible results.
• Stem Cell Expansion & Regenerative Medicine
  • Enhances iron regulation and metabolic activity in induced pluripotent stem cells (iPSC), mesenchymal stem cells (MSC), and embryonic stem cells (ESC).
  • Supports long-term stem cell maintenance and differentiation without reliance on animal components.
• Gene Therapy & Vaccine Production
  • Essential for virus propagation and recombinant protein expression, ensuring optimal iron homeostasis in cell culture.
  • Improves yield and stability of viral vectors, supporting AAV and lentiviral production.
• T Cell & Primary Cell Culture
  • Enhances immune cell proliferation and viability in T cell, NK cell, and primary cell cultures.
  • Provides a defined, serum-free alternative for cell therapy applications.

Technical Specifications

• Formulation: Lyophilized recombinant human transferrin
• Manufacturing: Produced in a state-of-the-art, ISO 9001:2015-certified facility in the USA
• Quality Assurance:
  • Fully recombinant and animal-origin-free production system
  • Stringent quality control processes ensure high batch-to-batch consistency
• Regulatory Compliance & Safety:
  • cGMP-compliant manufacturing
  • Plasma-free, pathogen-free, and chemically defined
  • Aligned with regulatory expectations for biopharmaceutical, regenerative medicine, and vaccine production applications

Why Choose Optiferrin?
Optiferrin is a high-performance alternative to plasma-derived transferrin, offering unparalleled purity, consistency, and regulatory compliance. Whether used for cell culture, biopharmaceutical manufacturing, or regenerative medicine, Optiferrin provides a safe, scalable, and animal-free solution for industrial and research applications.

• Artikelnummer: IVI777TRF029-10G
• Hersteller: InVitria
• Hersteller Artikelnummer: 777TRF029-10G
• Verpackungseinheit: 10G
• Mengeneinheit: STK