Product Description
OptiVERO® is a chemically defined, blood-free cell culture media system, specifically formulated to maximize VERO-based virus production in both 2D and 3D culture formats. Unlike traditional media that rely on plant hydrolysates or serum-derived components, OptiVERO provides a fully defined, scalable, and regulatory-friendly solution for vaccine manufacturing, virology research, and viral vector production.
Designed to reduce cell culture variability and accelerate virus manufacturing timelines, OptiVERO is supplied as a two-component kit consisting of a concentrated frozen protein supplement and a base media, allowing for greater flexibility and precise control over media composition.
Manufactured in an ISO 9001:2015-certified, cGMP-compliant facility in the United States, OptiVERO ensures batch-to-batch consistency, pathogen-free safety, and global regulatory compliance, making it an ideal solution for virology research and commercial vaccine production.
Advantages
- Optimized for VERO Cell-Based Virus Production
- Engineered for both 2D and 3D VERO cell culture systems, enabling scalable virus manufacturing.
- Enhances viral yield and production efficiency, improving process consistency for vaccine development.
- Accelerates research and development timelines, reducing variability in cell growth and virus propagation.
- Fully Chemically Defined & Blood-Free
- Does not contain undefined plant hydrolysates, ensuring greater consistency in bioprocessing.
- Blood-free, animal-origin-free formulation, reducing regulatory concerns and improving batch reproducibility.
- Eliminates reliance on undefined components, providing a more controlled environment for virus growth.
- Two-Component Media System for Greater Control
- Supplied as a two-component kit, including:
- Concentrated frozen protein supplement
- Base media
- Allows for precise customization and flexibility in media preparation, supporting both small-scale and large-scale bioproduction.
- Easily integrates into closed-system bioreactors, optimizing viral vector and vaccine development workflows.
- Animal-Origin-Free Assurance
- 100% chemically defined and animal-origin-free (AOF) – eliminating risks associated with serum-derived media.
- Manufactured using a non-animal, non-human host system, ensuring purity and reproducibility.
- Raw materials, manufacturing equipment, and packaging are fully animal-free, aligning with regulatory and ethical standards.
- Manufactured in the United States
- Produced in a tertiary-level, ISO 9001:2015-certified facility in the USA.
- Complete supply and manufacturing chain is owned and operated by InVitria, ensuring unmatched traceability and quality control.
- Batch-to-batch consistency for reliable integration into cGMP virology workflows.
Applications
- Vaccine Manufacturing & Virology Research
- Optimized for VERO cell-based virus propagation, ensuring high viral titers for vaccine production.
- Enables chemically defined, reproducible cell culture conditions, critical for regulatory compliance in vaccine development.
- Biopharmaceutical & Viral Vector Production
- Enhances AAV, lentivirus, and other viral vector production, supporting gene therapy applications.
- Reduces process variability, ensuring consistent virus yields across production batches.
- 2D & 3D Cell Culture Systems
- Designed to support both monolayer and suspension-based VERO cell cultures.
- Scalable for bioreactor-based virus production, ensuring efficient large-scale manufacturing.
Technical Specifications
- Formulation: Two-component system (Concentrated frozen protein supplement + Base media)
- Manufacturing: Produced in a state-of-the-art, ISO 9001:2015-certified facility in the USA
- Quality Assurance:
- Fully recombinant and animal-origin-free production system
- Stringent quality control processes ensure high batch-to-batch consistency
- Regulatory Compliance & Safety:
- cGMP-compliant manufacturing
- Plasma-free, pathogen-free, and chemically defined
- Aligned with regulatory expectations for biopharmaceutical and vaccine production applications
Why Choose OptiVERO?
OptiVERO is a high-performance, chemically defined alternative to traditional VERO cell media, offering superior virus yield, batch consistency, and regulatory compliance. Whether used for vaccine development, viral vector production, or virology research, OptiVERO provides a safe, scalable, and animal-free solution for industrial and research applications.