Clone Name: 25B2
Application Note: IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 32
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Uniprot ID: P49918
Antigen Species: Human
Immunogen: Prokaryotic recombinant antigen corresponding to a 116 amino acid region of the N-terminus of the p57 protein.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: cyclin dependent kinase inhibitor 1C