PAC-1, CAS 315183-21-2

Procaspase-3 activator

Product Type: Activator

CAS No.: 315183-21-2

MolecularFormula: C23H28N4O2

Molecular Weight: 392,5

Source: Synthetic

Purity: >98% (HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (35 mg/ml); or ethanol (15 mg/ml)

Appearance: Off-White powder

PubChem CID: 9675990

Scientific Background: PAC-1 is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3 (1); it is less potent at activating procaspase-7. It induces apoptosis in a variety of cancer cell lines by activation involving sequestering inhibitory zinc ions thus allowing procaspase-3 to autoactivate (2).

References: 1. Putt K.S., et al., (2006) Nat. Chem. Biol. 2:543.2. Peterson Q.P., et al., (2009) J. Mol. Biol. 388:144.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-569-25MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-569-25MG
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK