PD-1 (I126A), Fc fusion, Biotin-labeled (Human) HiP™ Recombinant

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Applications: Useful for the study of protein-protein interaction and in vitro and in vivo protein function.

Description: Human secreted Programmed Cell Death 1(PD-1)-Fc fusion protein, also known asCD279, PDCD1, and SLEB2, GenBankAccession No. NM_014143, amino acids25-167 with an I126A mutation, fused at theC-terminus with the Fc portion of humanIgG1, and C-terminal AviTag™, expressedin a HEK293 cell expression system andenzymatically biotin-labeled using AviTag™technology. MW = 44.5 kDa. This proteinruns at a higher MW by SDS-PAGE due toglycosylation.

Format: Aqueous buffer solution

Formulation: 8 mM Phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20%glycerol

Genbank: NM_014143

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal Fc fusion (Human IgG1), C-terminal Avi-tag™

Uniprot: Q15116

Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.

Biosafety Level: Not applicable (BSL-1)

References: 1. Freeman, G.J., et al., J. Exp. Med. 2000 Oct 2;192(7):1027-34.2. Dong, H., et al., Nat Med. 1999. Dec;5(12):1365-9.

• Artikelnummer: BPS71238-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71238-1
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK