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PerCP/Cyanine5.5 Anti-Mouse CD107a/LAMP-1 Antibody(1D4B), PerCP/Cy5.5, Rat, Monoclonal
PerCP/Cyanine5.5 Anti-Mouse CD107a/LAMP-1 Antibody(1D4B), PerCP/Cy5.5, Rat, Monoclonal
Artikelnummer
ELSE-AB-F1254J-200
Verpackungseinheit
100x2 Tests
Hersteller
Elabscience Biotechnology
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Swissprot: P11438.
Background: The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.
Abbre: Mouse CD107a.
Buffer: PBS with 0.05% Proclin300, 1% BSA.
Clone No: 1D4B.
Conjugation: PerCP/Cyanine5.5 .
Background: The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.
Abbre: Mouse CD107a.
Buffer: PBS with 0.05% Proclin300, 1% BSA.
Clone No: 1D4B.
Conjugation: PerCP/Cyanine5.5 .
| Artikelnummer | ELSE-AB-F1254J-200 |
|---|---|
| Hersteller | Elabscience Biotechnology |
| Hersteller Artikelnummer | ELA-E-AB-F1254J-100X2 |
| Verpackungseinheit | 100x2 Tests |
| Mengeneinheit | PAK |
| Reaktivität | Mouse (Murine) |
| Klonalität | Monoclonal |
| Methode | Flow Cytometry |
| Human Gene ID | 16783 |
| Wirt | Rat |
| Produktinformation (PDF) |
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| MSDS (PDF) |
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