PF-00446687, CAS 862281-92-3

Formulation: A solid

Formal Name: [(3S,4R)-4-(2,4-difluorophenyl)-1-(1,1-dimethylethyl)-3-pyrrolidinyl][(3R,5S)-4-hydroxy-3,5-dimethyl-4-phenyl-1-piperidinyl]-methanone

Purity: ≥98%

Formula Markup: C28H36F2N2O2

Formula Weight: 470,6

Shelf life (days): 1460

CAS Number: 862281-92-3

Notes: PF-00446687 is an agonist of melanocortin receptor 4 (MC4R).{68914} It selectively activates adenylyl cyclase in HEK293 cells expressing MC4R (EC50 = 0.012 µM) over HEK293 cells expressing MC1R, MC3R, or MC5R (EC50s = 1.02, 1.16, and 1.98 µM, respectively). PF-00446687 (1 mg/kg per day) increases time spent huddling and in close contact with chosen partners in prairie voles.{68915}

• Artikelnummer: CAY41739-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 41739-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK