PG-931, CAS 667430-81-1

Formulation: A neat oil

Formal Name: (2→7)-lactam N-acetyl-L-norleucyl-L-α-aspartyl-L-prolyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-lysyl-L-prolyl-L-valinamide

Purity: ≥98%

Formula Markup: C59H85N15O11

Formula Weight: 1180,4

Shelf life (days): 730

CAS Number: 667430-81-1

Notes: PG-931 is a peptide agonist of melanocortin receptor 4 (MC4R).{49951} It increases intracellular cAMP levels in CHO cells expressing MC4R with an EC50 value of 0.42 nM. PG-931 selectively binds to MC4R over MC3R and MC5R (IC50s = 0.58, 55, and 2.4 nM, respectively). It increases mean arterial pressure (MAP), pulse pressure, and respiratory rate in a rat model of hemorrhagic shock in a dose-dependent manner.{49952} It also prevents multiple organ damage and increases survival in the same model.

• Artikelnummer: CAY41551-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 41551-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK