Formulation: A neat solid
Formal Name: (2S,3S,4R)-2-aminooctadecane-16,16,17,17,18,18,18-d7-1,3,4-triol
Purity: ≥99% deuterated forms (d1-d7)
Formula Markup: C18H32D7NO3
Formula Weight: 324,6
Shelf life (days): 730
Notes: Phytosphingosine-d7 is intended for use as an internal standard for the quantification of phytosphingosine by GC- or LC-MS. Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans.{39177,39179} It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid (Item No. 22679) as an intermediate.{39084} Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors (mAChRs).{39105} It is essential in the heat stress response in S. cerevisiae.{13592}