PKM antibody (AT1B10)

Clone Name: AT1B10

Light Chain: Kappa

Application Note: WB: Recommended starting dilution is 1:1000.. ICC/IF: Recommended starting dilution is 1:250.. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 58

Form: Liquid

Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]

Uniprot ID: P14618

Antigen Species: Human

Immunogen: The clone AT1B10 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PKM4 protein.

Purification: Protein A Purified

Conjugation: Unconjugated

Full Name: pyruvate kinase M1/2

• Artikelnummer: GTX57604-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX57604-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG1
• Human Gene ID: 5315
• Wirt: Mouse