Conjugation: HRP: Horseradish Peroxidase
Description of Target: The specific function of the protein remains unknown.This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PNMA3
Key Reference: Wills,N.M., (2006) J. Biol. Chem. 281 (11), 7082-7088
Molecular Weight: 52kDa
Peptide Sequence: Synthetic peptide located within the following region:
RITGVGAVPLPASGNSFDVRPSQGYRRRRGRGQHRRGGVARAGSRGSRKRProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Paraneoplastic antigen Ma3
Protein Size: 463
Purification: Affinity Purified