Polyclonal Guinea-Pig anti-VIP

Immunogen: Synthetic human VIP (Peninsula, #7161)

Concentration: n/a

Storage buffer: Lyophilized; reconstitute in 100 µl dist. water

Additional info: VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP-producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.
Absorption with 10-100 ug immunogen per ml diluted antiserum abolishes the staining, while PHI does not.
Positive control: Stefanini-fixed frozen sections of rat intestine.

References: Messell, T. et al. Regul. Pept.1992; 38: 179–198/Karila, P. et al. Cell 1997;287:525-533

• Artikelnummer: SANPS249
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: PS249
• Verpackungseinheit: 50 µl (lyoph,)
• Mengeneinheit: STK
• Reaktivität: Human, Rat (Rattus), Pig (Porcine), Rabbit, Cat (Feline), Guinea Pig
• Klonalität: Polyclonal
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin)
• Wirt: Other
• Konjugat: Unconjugated