Polyclonal Rabbit anti-VIP

Immunogen: Purified porcine VIP

Concentration: n/a

Storage buffer: Lyophilized; reconstitute in 100 µl dist. water

Additional info: VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP-producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.
Absorption with 10-100 ug immunogen per ml diluted antiserum abolishes the staining, while PHI, secretin, glucagon, GIP, and CCK do not.Positive control: formalin-fixed paraffin sections of cat ileum.

References: Ny, L. et al. Histochem. J. 1994;26: 721–733 /Tagliafierro, G.et al. Cell Tissue Res. 1988;253: 23–8 /Karila, P. et al. Cell 1997; 287:525-33

• Artikelnummer: SANPS218
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: PS218
• Verpackungseinheit: 50 µl (lyoph,)
• Mengeneinheit: STK
• Reaktivität: Human, Rat (Rattus), Pig (Porcine), Cat (Feline)
• Klonalität: Polyclonal
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin)
• Wirt: Rabbit
• Konjugat: Unconjugated