PPM1H Antibody, Clone 10D2: ATTO 594

Human Anti-Human PPM1H Monoclonal IgG1

Target: PPM1H

Conjugate: ATTO 594

Product Type: Monoclonal

Clone Number: 10D2

Immunogen: Recombinant Human PPM1H Protein

Swiss-Prot: Q9ULR3

Purification: Protein G Purified

Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1mg/ml

Specificity: Detects ~55kDa

Cellular Localization: Intracellular

Tissue Specificity: Parathyroid gland

Scientific Background: PPM1H is an independent prognostic biomarker of non-small cell lung cancer (1). PPM1H acts as a key modulator of LRRK2 signaling by controlling dephosphorylation of Rab proteins (2). PPM1H is also suggested to be a gatekeeper to prevent excessive bone morphogenetic protein (BMP) signalling through dephosphorylation (3).

References: 1. Zhang W.Q., et al. (2021) Neoplasma. 68(5): 917-923. 2. Berndsen K., et al. (2019) 8:e50416. 3.Shen T., et al. (2014) Cell Res. 24(6): 727-741.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-616D-A594
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-616D-A594
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG1
• Human Gene ID: 57460
• Wirt: Mouse