PSMA antibody (k1H8)

PSMA antibody (k1H8)
Artikelnummer
GTX57558-100
Verpackungseinheit
100 μl
Hersteller
GeneTex

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Clone Name: k1H8

Light Chain: Kappa

Application Note: WB: 1:1000-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 84

Form: Liquid

Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]

Uniprot ID: Q04609

Antigen Species: Human

Immunogen: The clone k1H9 is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PSMA protein.

Purification: Protein G Purified

Conjugation: Unconjugated

Full Name: folate hydrolase 1
Mehr Informationen
Artikelnummer GTX57558-100
Hersteller GeneTex
Hersteller Artikelnummer GTX57558-100
Green Labware Nein
Verpackungseinheit 100 μl
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunofluorescence, Western Blotting, Flow Cytometry, Immunocytochemistry
Isotyp IgG1
Human Gene ID 2346
Wirt Mouse
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