Purified Anti-Human CD45RA Antibody(HI100), Mouse, Monoclonal

Abbreviation: CD45RA

Target Synonym: Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;

Conjugation: Unconjugated

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Clone NO.: HI100

UNIProt ID: P08575

Background: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/na?ve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Concentration: 0.5 mg/mL

• Artikelnummer: ELSE-AB-F1052A-25
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-F1052A-25
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Methode: Flow Cytometry
• Isotyp: Mouse IgG2b κ
• Human Gene ID: 5788
• Wirt: Mouse